Japanese by Example
Learning through examples in manga

Wide awake with 目が冴える

神経(しんけい)(たか)ぶって、(ねむ)れなくなる。また、眠気(ねむけ)がなくなる。

Unable to sleep due to heightened nerves. Also, to become no longer sleepy.

Goo Dictionary

()()える means to be wide awake, to be unable to fall asleep.

Examples

好きな子がめがねを忘れた » Volume 8 » Page 21